ATRIAL FIBRILLATION AND ISCHEMIC HEART DISEASE: HOW TO COMBINE ANTIPLATELET AND ANTICOAGULANT THERAPY, DEPENDING ON THE CLINICAL SITUATION?
نویسندگان
چکیده
منابع مشابه
Combination anticoagulant and antiplatelet therapy in atrial fibrillation patients.
The question of whether or not combination antithrombotic therapy is beneficial in terms of a reduction in fatal and non-fatal vascular events in atrial fibrillation (AF) is an important question which essentially remains unanswered. Original randomised controlled trials in AF patients examining the efficacy of combination oral anticoagulant (OAC) and antiplatelet therapy for stroke prevention ...
متن کاملReconsidering combined antiplatelet and anticoagulant therapy in atrial fibrillation.
ith the publication in 1989 of the first large randomized ontrolled trial of warfarin in atrial fibrillation (1), the role f anticoagulation for preventing stroke in this arrhythmia ecame established. Subsequent trials, published during the ollowing decade, confirmed the efficacy of the coumarin nticoagulants and demonstrated that stroke risk was a unction not only of the arrhythmia but also of...
متن کاملAnticoagulant and Antiplatelet Therapy in Patients with Atrial Fibrillation and Coronary Artery Disease
Anticoagulation represents the mainstay of therapy for most patients with atrial fibrillation. Patients on oral anticoagulation often require concomitant antiplatelet therapy, mostly because of coronary artery disease. After coronary stent implantation, dual antiplatelet therapy is necessary. However, the combination of oral anticoagulation and antiplatelet therapy increases the bleeding risk. ...
متن کاملAntiplatelet therapy for ischemic heart disease.
Rupture or injury of an atherosclerotic coronary arterial plaque — as occurs spontaneously in patients with an acute coronary syndrome or as the result of a percutaneous coronary intervention — serves as a nidus for platelet aggregation and thrombus formation, which, in turn, may cause myocardial infarction or death. Activation of the platelet-surface glycoprotein IIb/IIIa receptor is the final...
متن کاملapproach to antiplatelet and anticoagulant therapy before endoscopic procedures
the use of anticoagulant and antiplatelet agents has become more prevalent during the past decades. these drugs may potentially cause gastrointestinal (gi) bleeding. thus, there is an increasing need for gi endoscopy in patients who take these medications. in patients who take anticoagulant and antiplatelet agents, the appropriate conditions under which endoscopic procedures should be performed...
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ژورنال
عنوان ژورنال: Rational Pharmacotherapy in Cardiology
سال: 2016
ISSN: 2225-3653,1819-6446
DOI: 10.20996/1819-6446-2016-12-2-191-195